Detecting and monitoring biological processes with isothermal calorimetry has been shown to be an accurate analytical technique and is proportional to the rate at which a given chemical or physical process takes place. The development of modern isothermal microcalorimeters has made the measurements of sub-microwatt amounts of heat flow possible accurate and reproducible. As a…
In this TA Instruments sponsored webinar, Dr. Nichola Garbett discusses the emerging technique of using high sensitivity DSC analysis of blood plasma for plasma proteome research, and as a clinical diagnostic tool.
High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific interactions and chemical functionalities to the enthalpy and entropy…
Tribology complements rheology, providing information on solid-solid interactions that adds insight to the bulk fluid measurements of rheology. Tribology is especially concerned with quantifying the coefficient of friction as a function of sliding speed and load force, under dry or lubricated conditions. This provides useful information about lubrication, wear, tactility, and mouthfeel.
The combination of optical microscopy with rheological tests enables direct observation of material structure under shear deformation. This provides critical information that can help understand, predict, and tune the material response under processing, storage, or end-use conditions.
