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Thermodynamic Rules To Achieve High Binding Affinity & Selectivity

High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific interactions and chemical functionalities to the enthalpy and entropy…

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Thermal Analysis for Printed Circuit Boards (PCBs)

消费者兴趣和可持续性发展目标导致对电动汽车的需求飙升。美国的目标是,到 2030 年时电动汽车销量占总市场的 50%,但 99% 的电动汽车电池的原材料和零部件材料均在国外生产。1, 2 采购外国制造的材料和电池已经给该行业带来了挑战。2022 年 3 月,由于俄罗斯入侵乌克兰,电池的主要原料镍的价格暴涨。3

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