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Thermodynamic Rules To Achieve High Binding Affinity & Selectivity

High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific interactions and chemical functionalities to the enthalpy and entropy…

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TMA 450

TMA 450 Discover the World’s Finest Thermomechanical Analyzer The TMA 450 delivers Superior Performance, Unmatched Sensitivity & Maximum Versatility.    << View all Thermal Analyzers DescriptionSpecificationsTechnologyAccessoriesSoftwareApplicationsResources TA Instruments invites you to experience the finest in Thermomechanical Analyzers, the Discovery TMA 450. Discover the advanced engineering and attention to detail that provides enhancements in every aspect of…

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Trade In and Save

Trade in your current TA or competitive Thermogravimetric Analyzer or Simultaneous DSC/TGA system and SAVE up to 40% on a new Discovery system! No other vendor has introduced more new TGA technology over the last 12 months than TA Instruments. The advanced engineering and attention to detail on the New Discovery TGA and SDT systems provides…

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