In this TA Webinar, Professor Nand Kishore discusses how to best discover and interpret protein folding, ligand binding, aggregation and molecular partitioning in self assemblies. Tribology complements rheology, providing information on solid-solid interactions that adds insight to the bulk fluid measurements of rheology. Tribology is especially concerned with quantifying the coefficient of friction as a…
<< View all Application Notes ABSTRACT: Thermal stability signatures of biological fluids, comprised of a complex milieu of protein can be measured using differential scanning calorimetry (DSC). The DSC is a powerful tool in monitoring changes in the protein equilibrium that is perturbed by disease or cancer through amplification, modification, or multiple interactions of proteins…
<< View all Application Notes ABSTRACT Isothermal microcalorimetry is a simple method of determining the effect an electrolyte additive or additive combination has on the parasitic reactions occurring in a lithium-ion battery as a function of state of charge. In this study, high resolution isothermal microcalorimetry using a TAM III equipped with 12 microcalorimeters is…
<< View all Application Notes ABSTRACT Nanocomposite thermites include a reactive metal, in most cases aluminum, mixed on the nano-scale with a metal oxide. The nano-scale mixing achieved by ball-milling produces a highly developed and unusual interface area between reactive components. The high interface area assures a high reaction rate, attractive for propellants, explosives, and…
<< View all Application Notes ABSTRACT: We describe here a method using differential scanning calorimetry (DSC) to determine the energy of biomolecular halogen bonds (X-bonds) in a DNA system. This system is unique because we are able to isolate the energetics of a specific molecular interaction from the thermodynamic properties of an entire system. To…
<< View all Application Notes INTRODUCTION Pressure Perturbation Calorimetry (PPC) is a technique for determination of thermal and volumetric properties of macromolecules. These properties include the partial molar thermal cubic expansion coefficient (ᾱ, Equation 1, [1]) and the relative partial molar volume (∆V/V, Equation 2, [2]) of the macromolecule as functions of temperature. These parameters…
<< View all Application Notes ABSTRACT: Thermal stability signatures of biological fluids, comprised of a complex milieu of protein can be measured using differential scanning calorimetry (DSC). The DSC is a powerful tool in monitoring changes in the protein equilibrium that is perturbed by disease or cancer through amplification, modification, or multiple interactions of proteins…
<< View all Application Notes INTRODUCTION All biochemical reactions involve recognition, binding and the formation of non-covalent complexes. Since the characterization of binding events is central to understanding any physiological process at the molecular level, biochemical and biomedical research requires methodologies for precisely analyzing binding reactions. Isothermal titration calorimetry (lTC) is rapidly becoming the method…
<< View all Application Notes Keywords: structured fluids, sol gel transition, solution, yield stress, thixotropy, viscosity, mechanical stability, shelf life, flow curve, inks, cosmetics, dispersions, food AAN016
Understanding Rheology of Thermoplastic Polymers GENERAL CONSIDERATIONS Rheological testing of thermoplastic materials can be performed on both solid samples and on melts. This is important because the choice of material form and physical state is more than a matter of convenience: Product performance issues usually are related to solid samples properties; process ability issues…
Application of Rheology of Polymers INTRODUCTION TO THE APPLICATION OF POLYMER RHEOLOGY Polymers are viscoelastic fluids, which behave viscous or elastic, depending on how fast they flow or are deformed in the process. The silicone putty test is a good demonstration of this pheno-menon (Figure 1). If a ball of silicone is subjected to a…
