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Thermodynamic Rules To Achieve High Binding Affinity & Selectivity

High affinity and selectivity are two essential properties of drug molecules. Since the binding affinity is determined by the sum of enthalpic and entropic contributions, extremely high affinity necessitates optimization of both contributions to binding. An efficient approach requires accurate prediction of the contributions of specific interactions and chemical functionalities to the enthalpy and entropy…

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An Introduction to Tribo-Rheometry: Quantifying Friction

Tribology complements rheology, providing information on solid-solid interactions that adds insight to the bulk fluid measurements of rheology. Tribology is especially concerned with quantifying the coefficient of friction as a function of sliding speed and load force, under dry or lubricated conditions. This provides useful information about lubrication, wear, tactility, and mouthfeel.

Discovery HR-3

The new Discovery Series Hybrid Rheometer (DHR) represents the latest technological breakthroughs from the world leader in rheology. It combines a patented advanced drag cup motor, a second generation magnetic bearing, force rebalance transducer (FRT), and the new patent-pending True Position Sensor (TPS) in a single-head Hybrid rheometer. The DHR has unprecedented performance specification and delivers unsurpassed direct strain control, direct stress control, and normal force measurement accuracy.

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Discovery HR-2

The new Discovery Series Hybrid Rheometer (DHR) represents the latest technological breakthroughs from the world leader in rheology. It combines a patented advanced drag cup motor, a second generation magnetic bearing, force rebalance transducer (FRT), and the new patent-pending True Position Sensor (TPS) in a single-head Hybrid rheometer. The DHR has unprecedented performance specification and delivers unsurpassed direct strain control, direct stress control, and normal force measurement accuracy.

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Discovery HR-1

The new Discovery Series Hybrid Rheometer (DHR) represents the latest technological breakthroughs from the world leader in rheology. It combines a patented advanced drag cup motor, a second generation magnetic bearing, force rebalance transducer (FRT), and the new patent-pending True Position Sensor (TPS) in a single-head Hybrid rheometer. The DHR has unprecedented performance specification and delivers unsurpassed direct strain control, direct stress control, and normal force measurement accuracy.

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Dynamic Mechanical Analysis

Dynamic Mechanical Analysis (DMA) The DMA Mode adds a new dimension for testing of solid and soft-solid materials. DescriptionSpecifications & FeaturesApplications Dynamic Mechanical Analysis (DMA) The DMA Mode adds a new dimension for testing of solid and soft-solid materials. Now in addition to the most sensitive and accurate rotational shear measurements, the Discovery Hybrid Rheometer…

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STA 504

STA 504 Simultaneous Thermal Analyzer The STA504 provides simultaneous measurement of weight change (TGA) and heat flow (DSC) on a sample from -160 to 1650˚C.   OverviewSpecificationsInstrument design The STA504 provides simultaneous measurement of weight change (TGA) and heat flow (DSC) on a sample from -160 to 1650˚C. The STA504 features a vertical balance design…

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DXF 500

The Discovery Xenon Flash (DXF) source module employs a High Speed Xenon-pulse Delivery source (HSXD) which has considerably higher efficiency, lower costs and less maintenance than equivalent systems. A reflective optic configuration of our design effectively harnesses the power of a Xenon flash tube and, with the aid of proprietary wave guides, delivers it to the specimen inside the Environmental Module. DXF 500 produces a pulse width of 400 μs to 600 μs and uniformly concentrates the power from the flash source directly on the entire face of the specimen. Due to this optimized optical arrangement and the broad light spectrum, specimens as large as 25 mm in diameter can be illuminated with sufficient energy to make a high-accuracy measurement. The use of large samples diminishes errors associated with inhomogeneity and permits representative measurements of poorly dispersed composites.

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DXF 200

The Discovery Xenon Flash DXF 200 employs a High Speed Xenon-pulse Delivery source (HSXD) with considerably lower cost and less maintenance than a laser and generates equivalent results. A reflective optic configuration of our design effectively harnesses the power of a Xenon flash tube and, with the aid of proprietary wave guides, delivers it to the specimen inside the Environmental Module. DXF 200 produces a pulse width that is shorter (400 μs to 600 μs) than many commercial laser-based systems, while uniformly concentrating sufficient power from the flash source directly on the entire face of the specimen. Due to this optimized optical arrangement and the broad light spectrum, specimens as large as 25 mm in diameter can be illuminated with sufficient energy to make a high-accuracy measurement. The use of large samples diminishes errors associated with inhomogeneity and permits representative measurements of poorly dispersed composites.

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